An Oral Botanical Supplement Improves Small Intestinal Bacterial Overgrowth (SIBO) and Facial Redness: Results of an Open-Label Clinical Study.

What Was Tested

Researchers studied Copper (Supplement) in the context of sibo in this clinical trial publication.

The objective of this study was to assess how the use of an oral botanical regimen may modulate the gut microbiome, facial erythema, and intestinal permeability in those with SIBO.

Lactulose breath tests were administered at baseline, weeks 6, 10, and 14 to assess for SIBO status.

Why It Was Studied

Small intestinal bacterial overgrowth (SIBO) is a common, yet underdiagnosed, gut condition caused by gut dysbiosis.

Who Took Part

PubMed indexes the participants as adults, middle-aged adults and older adults, both men and women.

This was an open-label prospective study of adults that had lactulose breath test-confirmed SIBO.

Participants received a 10-week oral supplementation of a Biocidin liquid tincture and GI Detox+.

How the Study Was Run

In design terms this was an open-label study.

Being open-label, the Copper (Supplement) study did not mask who received what.

A high-resolution photographic analysis system was utilized to analyze changes in facial erythema.

Stool sample collections and venipuncture were performed to analyze the gut microbiome and intestinal permeability.

What Was Measured

Small intestinal bacterial overgrowth (SIBO) is a common, yet underdiagnosed, gut condition caused by gut dysbiosis.

The subject headings attached to it are Gastrointestinal Microbiome, Dietary Supplements, Breath Tests, Intestine, Small, Erythema, Blind Loop Syndrome and Face.

The authors tagged it with the keywords SIBO, botanical, facial erythema, gut microbiome, gut–skin axis and rosacea.

What This Means in Plain Language

The paper is an open-label study of Copper (Supplement) in people with sibo.

The abstract goes on to report its results in about 13 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2024 (Nutrients), a journal based in Switzerland.

More context: the Copper (Supplement) compound page, SIBO research.