Evaluation of gastric content in fasting patient during semaglutide use: an observational study

What Was Tested

This observational study looks at Semaglutide.

To investigate the effect of semaglutide on gastric content by gastric ultrasonography in volunteers.

The main objective was to determine whether the stomach was full or not.

Why It Was Studied

The evident influence of GLP-1 agonists as semaglutide on gastric emptying even in adherence to recommended fasting protocols instigates debates.

Who Took Part

The abstract describes 30 volunteers taking part.

PubMed indexes the participants as adults and middle-aged adults, both men and women.

The intervention group consisted of 15 volunteers who had used semaglutide within the last 7 days, whereas the control group consisted of 15 volunteers who had never used semaglutide.

How the Study Was Run

The present study is an observational, cross-sectional, and single-center study.

What Was Measured

Topics PubMed links to this paper include Glucagon-Like Peptides, Cross-Sectional Studies, Fasting, Gastric Emptying, Gastrointestinal Contents, Ultrasonography and Hypoglycemic Agents.

The authors tagged it with the keywords Fasting patient, GLP-1 agonists, Gastric content and Semaglutide.

What This Means in Plain Language

This is an observational study of Semaglutide in 30 volunteers.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2025 (Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery), a journal based in United States.

More context: the Semaglutide compound page, all human trials.