← Human Trials & Peer-Reviewed Studies

Copper biomarkers and their relationship with parameters of insulin resistance in obese women

Plain-language guide to PMID 39392553 (2025): observational study of Copper (Supplement) in 203 women, insulin resistance, prediabetes & type 2 diabetes.

Key Facts

PMID
39392553
Journal
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine
Year
2025
Study type
Observational Study
Authors
da Silva NC et al. (15 authors)
DOI
10.1007/s10534-024-00645-7

What This Study Did, in Plain Language

What Was Tested

This observational study looks at Copper (Supplement) in the context of insulin resistance, prediabetes & type 2 diabetes.

The objective of this study was to evaluate the copper nutritional status and its relationship with parameters of glycemic control in women with obesity.

Why It Was Studied

An observational case-control clinical study involving 203 women aged between 20 and 50 years, divided into two groups: obese (n = 84) and eutrophic (n = 119).

It was observed that women with obesity had higher copper concentrations in plasma and lower concentrations in erythrocytes when compared to the control group.

Who Took Part

The abstract describes 203 women taking part.

By PubMed's age tags, the people studied were young adults, adults and middle-aged adults, women only.

How the Study Was Run

Body weight, height and waist, hip and neck circumferences, dietary copper intake, copper biomarkers, determine ceruloplasmin activity and glycemic control parameters were measured.

What Was Measured

The subject headings attached to it are Copper, Insulin Resistance, Obesity, Biomarkers, Case-Control Studies, Blood Glucose and Insulin.

The authors tagged it with the keywords Nutritional status.

What This Means in Plain Language

This is an observational study of Copper (Supplement) in 203 women in people with insulin resistance, prediabetes & type 2 diabetes.

The publication is from 2025 (Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine), a journal based in Netherlands.

More context: the Copper (Supplement) compound page, Insulin resistance, prediabetes & type 2 diabetes research.

Our Notes on the Compound

Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.