← Human Trials & Peer-Reviewed Studies

Vitamin D Supplementation Does Not Enhance Gains in Muscle Strength and Lean Body Mass or Influence Cardiorespiratory Fitness in Vitamin D-Insufficient Middle-Aged Men Engaged in Resistance Training.

Plain-language guide to PMID 39408324 (2024): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc, muscle gain, sarcopenia & building muscle after 40.

Key Facts

PMID
39408324
Journal
Nutrients
Year
2024
Study type
Randomized Controlled Trial
Authors
Savolainen L et al. (11 authors)
DOI
10.3390/nu16193356

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc in the context of muscle gain, sarcopenia & building muscle after 40.

Who Took Part

PubMed indexes the participants as adults and middle-aged adults, men only.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

What Was Measured

The subject headings attached to it are Muscle Strength, Cardiorespiratory Fitness, Resistance Training, Vitamin D, Dietary Supplements, Vitamin D Deficiency and Body Composition.

Author keywords: HOMA-IR, cortisol, growth hormone, inflammatory status, insulin and parathormone.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in people with muscle gain, sarcopenia & building muscle after 40.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2024 (Nutrients), a journal based in Switzerland.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Muscle gain, sarcopenia & building muscle after 40 research.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.