The association between the triglyceride-glucose index and vitamin D status: a systematic review and meta-analysis.

What It Covers

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a meta-analysis.

This study aims to explore the association between the triglyceride-glucose (TyG) index and vitamin D status to enhance their understanding of how vitamin D status relates to metabolic health and to provide evidence for the early diagnosis of vitamin D deficiency (VDD) using the TyG index.

Who the Included Studies Covered

The researchers used a random-effects model considering the inherent clinical heterogeneity among the studies, and assessed statistical heterogeneity with the Cochrane Q test and I2 statistic, complemented by subgroup analyses and sensitivity analysis.

How the Review Was Done

The researchers conducted a comprehensive search in various databases, including PubMed, Web of Science, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), China Biology Medicine disc, China Science and Technology Journal Database, and Wanfang Data to gather articles published from the inception of these databases until February 19, 2024.

The researchers assessed the quality of included studies using the Newcastle-Ottawa Scale (NOS) for case-control studies and the Agency for Healthcare Research and Quality (AHRQ) methodology checklist for cross-sectional studies.

Statistical analyses in this study were conducted using conversion methods for non-standard data formats and consolidation techniques for combining multiple groups.

The Fisher transformation method was used for correlation coefficients.

What Was Measured

Topics PubMed links to this paper include Biomarkers, Blood Glucose, Diabetes Mellitus, Type 2, Triglycerides, Vitamin D and Vitamin D Deficiency.

Author keywords: Meta-analysis, Metabolic health and Triglyceride-glucose index.

What This Means in Plain Language

This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2024 (BMC endocrine disorders), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.