A Comparative Study of Vitamin D Serum Levels in Monosymptomatic Enuretic Children and Non-Enuretic Children.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this observational study publication.

To evaluate the relationship between Vitamin D deficiency and nocturnal enuresis and to study the correlation between Vitamin D deficiency and urine osmolality, which is an indirect indicator of ADH deficiency.

Why It Was Studied

The pathogenesis of enuresis is complex.

It is related to low functional bladder capacity, nocturnal bladder overactivity, and high arousal threshold, and it is also related to the immaturity of the central nervous system.

Who Took Part

According to the abstract, 60 children were involved.

The age groups tagged for this paper are young children and children, both men and women.

The study included 60 children with primary monosymptomatic nocturnal enuresis selected randomly and 60 healthy children as a control group.

How the Study Was Run

This is a case-control study that started in February 2020 and ended in August 2020 in their tertiary hospital.

The researchers compared Vitamin D levels, nocturnal polyuria, and nocturnal urine osmolality among both groups.

What Was Measured

The subject headings attached to it are Biomarkers, Case-Control Studies, Nocturnal Enuresis, Osmolar Concentration, Polyuria, Vitamin D and Vitamin D Deficiency.

Author keywords: nocturnal polyuria and urine osmolality.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc in 60 children.

Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2025 (Neurourology and urodynamics), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.