← Human Trials & Peer-Reviewed Studies
Weight Loss Induces Changes in Vitamin D Status in Women With Obesity But Not in Men: A Randomized Clinical Trial.
Plain-language guide to PMID 39530599 (2025): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 195 individuals, fat loss, obesity & body recomposition.
Key Facts
- PMID
- 39530599
- Journal
- The Journal of clinical endocrinology and metabolism
- Year
- 2025
- Study type
- Randomized Controlled Trial
- Authors
- Holt R et al. (15 authors)
- DOI
- 10.1210/clinem/dgae775
- Registered trial
- NCT04122716
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc in the context of fat loss, obesity & body recomposition.
The aim of this study was to investigate the effects of weight loss on vitamin D status in individuals with obesity, and secondarily, whether vitamin D metabolism differs between women and men.
Who Took Part
The abstract describes 195 individuals taking part.
The age groups tagged for this paper are adults and middle-aged adults, both men and women.
How the Study Was Run
In design terms this was a randomized and placebo-controlled study.
The individuals were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
Some individuals received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.
What Was Measured
The subject headings attached to it are Weight Loss, Obesity, Vitamin D, Caloric Restriction, Liraglutide, Sex Factors and Vitamin D Deficiency.
Author keywords: GLP-1 receptor agonist, glucagon-like peptide-1 and sex differences.
What This Means in Plain Language
The paper is a randomized and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 195 individuals in people with fat loss, obesity & body recomposition.
Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2025 (The Journal of clinical endocrinology and metabolism), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, Fat loss, obesity & body recomposition research.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.