Comparative effects of three mucoadhesive gels containing lidocaine, zinc acetate, and tannic acid on the gag reflex of dental patients: a randomized double-blind clinical trial.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

This study aimed to compare the effects of three mucoadhesive gels containing lidocaine, zinc acetate, and tannic acid on the gag reflex of dental patients.

Who Took Part

The study group was 228 patients.

The age groups tagged for this paper are young adults, adults and middle-aged adults, both men and women.

This randomized double-blind clinical trial was conducted on 228 dental patients with gag reflex.

The severity of the gag reflex of patients was initially scored by stimulating their soft and hard palate with a radiographic film using a 0-5 visual analog scale.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

Data were analyzed by ANOVA and paired t-test for the single group comparison (alpha = 0.05).

What Was Measured

The subject headings attached to it are Lidocaine, Tannins, Gels, Gagging, Zinc Acetate, Anesthetics, Local and Polyphenols.

The authors tagged it with the keywords Tannic acid.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 228 patients.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2024 (BMC oral health), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.