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Unraveling the Relationship Between Vitamin D and Noncommunicable Diseases: A Systemic Review and Meta-Analysis.

Plain-language guide to PMID 39777920 (2025): meta-analysis of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
39777920
Journal
Public health nursing (Boston, Mass.)
Year
2025
Study type
Meta-Analysis
Authors
Dumbre D et al. (3 authors)
DOI
10.1111/phn.13521

What This Paper Covers, in Plain Language

What It Covers

Researchers studied Vitamin D, K2, Magnesium and Zinc in this meta-analysis publication.

In meta-analysis data combined from multiple observational Unraveling the Relationship Between Vitamin D and Noncommunicable Diseases-A Systemic Review and Meta-Analysis studies to evaluate the relationship between vitamin D insufficiency and health outcomes.

Statistical techniques, such as calculating effect sizes and constructing confidence ranges, are employed to determine combined outcomes and investigate possible causal connections.

Why It Was Studied

Subclinical vitamin D insufficiency is frequent in both developing and developed countries.

Even after rickets was eliminated in the 1930s by fortifying milk, up to 1 billion people worldwide suffer from subclinical vitamin D deficiency (VDD).

How the Review Was Done

The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol was applied when conducting a systematic review.

Relevant studies published between 2010 and 2023 were found by searching databases such as Web of Science, Scopus, and PubMed.

To find correlations between deficiency of vitamin D and NCDs, data was extracted from the studies and analyzed using the Mixed Method Appraisal Tools (MMAT).

What Was Measured

PubMed files the paper under topics including Noncommunicable Diseases, Vitamin D and Vitamin D Deficiency.

The authors tagged it with the keywords anemia, autoimmune disorder, cancer, cardiovascular diseases, diabetes and hypertension.

What This Means in Plain Language

This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 8 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2025 (Public health nursing (Boston, Mass.)), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.