The effect of preoperative topical magnesium sulfate spraying in the oropharyngeal region on postoperative sore throat following gynecological laparoscopic surgery: a randomized clinical trial.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

This study aimed to investigate the impact of preoperative topical magnesium sulfate spraying in the oropharyngeal region on postoperative sore throat following gynecological laparoscopic surgery.

Why It Was Studied

Postoperative sore throat is a common complication following general anesthesia.

The study was registered at Chictr.org.cn with the number ChiCTR2400087240 on 07/23/2024.

Who Took Part

According to the abstract, 58 patients were involved.

The age groups tagged for this paper are adults and middle-aged adults, women only.

The study included 58 patients scheduled for gynecologic laparoscopic surgery at Xuzhou Medical University Affiliated Hospital.

Patients were randomly assigned to either the magnesium sulfate group or the control group, with 29 patients in each group.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Neither the patients nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

The primary outcome measure was the overall incidence of postoperative sore throat 48 h after surgery.

What Was Measured

PubMed files the paper under topics including Pharyngitis, Magnesium Sulfate, Laparoscopy, Postoperative Complications, Gynecologic Surgical Procedures, Administration, Topical and Preoperative Care.

The authors tagged it with the keywords Endotracheal intubation, General anesthesia and Postoperative sore throat.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 58 patients.

Its findings take up roughly 3 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2025 (BMC anesthesiology), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.