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Identifying risk factors for vomiting during diarrhea: A secondary analysis of a randomized trial of zinc supplementation.
Plain-language guide to PMID 39806793 (2025): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 4500 children.
Key Facts
- PMID
- 39806793
- Journal
- Journal of pediatric gastroenterology and nutrition
- Year
- 2025
- Study type
- Randomized Controlled Trial
- Authors
- Edwards JG et al. (15 authors)
- DOI
- 10.1002/jpn3.12441
- Registered trial
- NCT03078842
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.
Who Took Part
The abstract describes 4500 children taking part.
By PubMed's age tags, the people studied were infants and young children, both men and women.
The researchers performed a secondary data analysis of 4500 children aged 6-59 months with an acute episode of diarrhea (<72 h before enrollment) in a randomized, double-blind controlled trial in India and Tanzania.
How the Study Was Run
The researchers set it up as a randomized and double-blind study.
The children were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
Neither the children nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.
What Was Measured
PubMed files the paper under topics including Acute Disease, Dehydration, Diarrhea, Dietary Supplements, India, Risk Factors and Tanzania.
Author keywords: children.
What This Means in Plain Language
The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 4500 children.
With several hundred people or more, it is a fairly large study for this kind of research.
Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2025 (Journal of pediatric gastroenterology and nutrition), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.