Impact of 24-week supervised concurrent exercise on S-Klotho and vitamin D levels: A randomized controlled trial.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

This study aimed to investigate the effects 24 weeks of supervised exercise training at different intensities on S-Klotho and 25-hydroxyvitamin D plasma levels in young adults.

Why It Was Studied

This report was based on a secondary analysis from the ACTIBATE single-center unblinded randomized controlled trial (ClinicalTrials.gov ID: NCT02365129).

The participants were randomly assigned to 3 different groups: (i) concurrent exercise training program based on the international physical activity recommendations at vigorous intensity (Ex-Vigorous group), (ii) at moderate intensity (Ex-Moderate group), and (iii) control group (no exercise).

Who Took Part

The study group was 144 adults.

PubMed indexes the participants as teenagers, young adults and adults, both men and women.

How the Study Was Run

In design terms this was a randomized study.

The adults were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

What Was Measured

This report was based on a secondary analysis from the ACTIBATE single-center unblinded randomized controlled trial (ClinicalTrials.gov ID: NCT02365129).

Topics PubMed links to this paper include Vitamin D, Klotho Proteins, Glucuronidase and Exercise.

The authors tagged it with the keywords Aerobic training, concurrent training, exercise physiology and strength training.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 144 adults.

The publication is from 2024 (Journal of sports sciences), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.