Efficacy and safety of standardized lime peel supplement in adults with sleep disturbance: A randomized, double-blind, placebo-controlled, polysomnographic study.

What Was Tested

The paper reports a study of Copper (Supplement), published as a randomized controlled trial.

This study aimed to evaluate the effects of SLPS in adults experiencing sleep disturbances.

Why It Was Studied

Citrus peels are rich in flavonoids with potential sedative-hypnotic effects; however, these effects have not yet been fully explored.

Who Took Part

The abstract describes 80 subjects taking part.

By PubMed's age tags, the people studied were adults and middle-aged adults, both men and women.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Random assignment meant chance, not the researchers, decided who got Copper (Supplement) and who got the comparison, which limits bias.

Neither the subjects nor the staff measuring them knew who was on Copper (Supplement), so expectations could not easily colour the readings.

A placebo (an inactive look-alike) gave the Copper (Supplement) group a baseline to be compared against.

What Was Measured

The subject headings attached to it are Polysomnography, Sleep Wake Disorders, Dietary Supplements, Citrus, Plant Extracts, Sleep and Hypnotics and Sedatives.

Author keywords: Citrus peels, Insomnia, Sedative-hypnotics, Sleep latency and Standardized lime peel supplement.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Copper (Supplement) in 80 subjects.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2025 (Phytomedicine : international journal of phytotherapy and phytopharmacology), a journal based in Germany.

More context: the Copper (Supplement) compound page, all human trials.