Comparison of Preoperative Topical Magnesium Sulfate Spraying and Magnesium Sulfate Gargling for the Prevention of Postoperative Sore Throat after Tracheal Intubation: A Randomized, Double-Blind, Non-Inferiority Trial.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

Who Took Part

The abstract describes 236 participants taking part.

PubMed indexes the participants as adults and middle-aged adults, both men and women.

236 Participants were randomly allocated to either the magnesium sulfate spray group (Group A) or the magnesium sulfate gargle group (Group B), with 118 patients in each group.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

What Was Measured

Topics PubMed links to this paper include Administration, Topical, Intubation, Intratracheal, Magnesium Sulfate, Pharyngitis and Postoperative Complications.

The authors tagged it with the keywords endotracheal intubation, general anaesthesia and postoperative sore throat.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 236 participants.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2025 (Drug design, development and therapy), a journal based in New Zealand.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.