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Effects of Maternal Vitamin D Levels on Prematurity: Feasibility Study in a Multicenter Observational Pilot.

Plain-language guide to PMID 40218918 (2025): multicenter and pilot observational study of Vitamin D, K2, Magnesium and Zinc in 1800 participants.

Key Facts

PMID
40218918
Journal
Nutrients
Year
2025
Study type
Observational Study
Authors
Barbosa O et al. (9 authors)
DOI
10.3390/nu17071160
Registered trial
NCT06292195

What This Study Did, in Plain Language

What Was Tested

This observational study looks at Vitamin D, K2, Magnesium and Zinc.

The project includes a large-scale multicenter observational study, targeting a minimum initial sample size of 1800 participants.

This paper describes the pilot study aimed at assessing the feasibility of the full-scale study.

Who Took Part

According to the abstract, 1800 participants were involved.

The age groups tagged for this paper are adults, women only.

Feasibility was assessed through predefined outcome indicators and success criteria.

How the Study Was Run

The researchers set it up as a multicenter and pilot study.

Running at several centres spread the Vitamin D, K2, Magnesium and Zinc study over different clinics and patient groups.

It is described as a pilot, a small early test of whether a larger Vitamin D, K2, Magnesium and Zinc study would be practical.

What Was Measured

This paper describes the pilot study aimed at assessing the feasibility of the full-scale study.

Data collection included 67 parameters: 37 obtained from a questionnaire and 30 from clinical records, with particular focus on maternal 25(OH)D levels and maternal-infant health outcomes.

PubMed files the paper under topics including Pilot Projects, Feasibility Studies, Vitamin D Deficiency, Vitamin D, Premature Birth, Pregnancy Complications and Infant, Premature.

The authors tagged it with the keywords feasibility study, maternal vitamin D levels, prematurity and public health.

What This Means in Plain Language

The paper is a multicenter and pilot study of Vitamin D, K2, Magnesium and Zinc in 1800 participants.

With several hundred people or more, it is a fairly large study for this kind of research.

The publication is from 2025 (Nutrients), a journal based in Switzerland.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.