The Lebanese GRADE-based vitamin D guidelines: a paradigm for the MENA region.

What It Covers

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a systematic review.

The researchers followed the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology to assess the quality and certainty of evidence, and to develop recommendations.

Why It Was Studied

The Middle East and North Africa region are traditionally known as regions with a high prevalence of vitamin D deficiency.

The researchers developed guidelines on the screening and supplementation of adult Lebanese patients with vitamin D.

Who the Included Studies Covered

The age groups tagged for this paper are adults.

The researchers conducted a systematic review to gather global data on fracture (CRD42019129540), regional data on vitamin D trials (CRD42014010488), and on patients' values and preferences (CRD42022320022).

The researchers also complemented the latter with results from a cross-sectional local study.

How the Review Was Done

Their guideline panel consisted of clinical and methodology experts that formulated the guidelines questions.

What Was Measured

The subject headings attached to it are Vitamin D Deficiency, Lebanon, Vitamin D, Dietary Supplements, Mass Screening, Bone Density Conservation Agents and Osteoporotic Fractures.

The authors tagged it with the keywords GRADE methodology and Guidelines.

What This Means in Plain Language

This is a systematic review of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 8 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2025 (Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.