Prospective Multicenter Observational Study of Patients in Shock Treated with Vasopressin: VASOPRES Registry Study Protocol

What Was Tested

The paper reports a study of Vasopressin, published as a clinical study.

The main objective is to characterise the routine clinical practice of vasopressin (VASOPRES) use in the context of shock, collecting clinical, analytical and echocardiographic data.

Why It Was Studied

In cases of arterial hypotension and/or hypoperfusion that do not respond to fluid therapy, the administration of intravenous catecholamines, especially norepinephrine, is usually the treatment of choice.

The Vasopres registry has already been approved by the Clinical Research Ethics Committee of the Hospital Universitario de La Princesa, Madrid (registration number 5596) in May 2024.

Who Took Part

The VASOPRES Registry is a prospective multicentre observational study, in which critical care anaesthesia units from all over Spain will participate, collecting data on patients over 18 years of age in whom treatment with vasopressin is initiated, regardless of the type of shock they present.

How the Study Was Run

The design is described as multicenter.

Running at several centres spread the Vasopressin study over different clinics and patient groups.

The timeline in the abstract includes 18 years.

The duration of the study is estimated at 24 months, starting from its approval by the Clinical Research Ethics Committee (CEIm).

What Was Measured

The subject headings attached to it are Observational Studies as Topic, Registries, Shock, Vasoconstrictor Agents and Vasopressins.

The authors tagged it with the keywords Hemodynamic support, Insuficiencia renal, Renal failure, Soporte hemodinámico, Soporte ventilatorio and Vasopresina.

What This Means in Plain Language

The paper is a multicenter study of Vasopressin over 18 years.

Its findings take up roughly 3 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2025 (Revista espanola de anestesiologia y reanimacion), a journal based in Spain.

More context: the Vasopressin compound page, all human trials.