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Evaluation of Zinc Oxide-Eugenol, Zinc Oxide-Propolis and Endoflas as an Obturating Materials in Primary Molar Pulpectomies - A Comparative Study.
Plain-language guide to PMID 40439208 (2025): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 50 children.
Key Facts
- PMID
- 40439208
- Journal
- Indian journal of dental research : official publication of Indian Society for Dental Research
- Year
- 2025
- Study type
- Randomized Controlled Trial
- Authors
- Singh S et al. (5 authors)
- DOI
- 10.4103/ijdr.ijdr_76_23
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.
To evaluate and compare the clinical and radiographic success of zinc oxide eugenol, Zinc oxide-Propolis, and endoflas as obturating materials in the pulpectomy of primary teeth at 3, 6 and 9 months of follow-up.
Why It Was Studied
The need to find the optimum root canal paste, however, was driven by the complex morphology of primary root canals and the desire for shorter therapy sessions.
Who Took Part
The abstract describes 50 children taking part.
The age groups tagged for this paper are young children and children, both men and women.
Pulpectomy of 60 nonvital primary molars was accomplished in 50 children aged 4-9 years.
How the Study Was Run
The researchers set it up as a randomized and double-blind study.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Neither the children nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.
Teeth were randomly divided into three equal groups of 20 molars according to the type of root canal filling material.
Pulpectomy was performed in a single or multiple visits depending on the condition of the tooth, and a stainless-steel crown was used for final restoration.
Clinical and radiographic results were evaluated double-blindly at baseline (1 week), and at 3, 6 and 9 months, while radiographic results were evaluated at baseline (1 week), and at 6 and 9 months.
Data were analysed using the Chi-square/Fisher's exact test, and the P value was set at 0.05.
What Was Measured
The need to find the optimum root canal paste, however, was driven by the complex morphology of primary root canals and the desire for shorter therapy sessions.
PubMed files the paper under topics including Tooth, Deciduous, Pulpectomy, Molar, Zinc Oxide-Eugenol Cement, Propolis, Root Canal Filling Materials and Zinc Oxide.
What This Means in Plain Language
The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 50 children.
The abstract goes on to report its results in about 2 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2025 (Indian journal of dental research : official publication of Indian Society for Dental Research), a journal based in India.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.