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A cross-sectional study on vitamin D deficiency and cardiac electrophysiology: Evaluating the frontal QRS-T angle.

Plain-language guide to PMID 40441193 (2025): observational study of Vitamin D, K2, Magnesium and Zinc in 357 individuals.

Key Facts

PMID
40441193
Journal
Medicine
Year
2025
Study type
Observational Study
Authors
Akyildiz Tezcan E et al. (2 authors)
DOI
10.1097/MD.0000000000042694

What This Study Did, in Plain Language

What Was Tested

This observational study looks at Vitamin D, K2, Magnesium and Zinc.

This study aimed to assess the influence of vitamin D deficiency on the frontal QRS-T (f[QRS-T]) angle on electrocardiograms, a potential marker of arrhythmic risk and cardiac mortality, to address a notable gap in the current understanding.

Why It Was Studied

Vitamin D deficiency is a global health issue, primarily recognized for its role in bone health and calcium absorption.

A total of 282 participants were grouped by vitamin D levels: vitamin D-deficient (<20 ng/mL, n = 185) and non-deficient (≥20 ng/mL, n = 97).

Who Took Part

The abstract describes 357 individuals taking part.

PubMed indexes the participants as adults, middle-aged adults and older adults, both men and women.

In this prospective cross-sectional study, 357 individuals were assessed, with 75 excluded (60 for not meeting criteria, 10 declined, 5 other reasons).

What Was Measured

A total of 282 participants were grouped by vitamin D levels: vitamin D-deficient (<20 ng/mL, n = 185) and non-deficient (≥20 ng/mL, n = 97).

After excluding 7 participants for incomplete tests, data from 275 (deficient: n = 180; non-deficient: n = 95) were analyzed.

Topics PubMed links to this paper include Cross-Sectional Studies, Vitamin D Deficiency, Electrocardiography, Vitamin D and Arrhythmias, Cardiac.

The authors tagged it with the keywords cardiovascular health, electrocardiogram and frontal QRS-T angle.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc in 357 individuals.

With several hundred people or more, it is a fairly large study for this kind of research.

The publication is from 2025 (Medicine), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.