Vitamin D3 supplementation enhances the effect of aerobic water-based training on physical fitness indices in obese and overweight menopausal women: A randomized controlled trial.

Plain-language guide to PMID 40735907 (2025): parallel-group randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID: 40735907
Journal: Women's health (London, England)
Year: 2025
Study type: Randomized Controlled Trial
Authors: Zaravar F et al. (5 authors)
DOI: 10.1177/17455057251361255

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

This parallel-group randomized controlled trial investigated the effects of water-based aerobic exercise training and vitamin D3 supplementation on body mass index (BMI) and physical performance in postmenopausal women who were overweight or obese and had insufficient or deficient levels of serum vitamin D.

Why It Was Studied

Some studies have examined the impact of exercise on obesity outcomes as part of a palliative care program.

Who Took Part

PubMed indexes the participants as middle-aged adults and older adults, women only.

This was an experimental study.

Forty women were randomly assigned to one of four groups: Water-based training + vitamin D (WTD), water-based training (WT), vitamin D (D), and control.

How the Study Was Run

The design is described as randomized and parallel-group.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

The Vitamin D, K2, Magnesium and Zinc group and the comparison group ran side by side rather than switching.

Measurements were taken before and after the intervention.

What Was Measured

Some studies have examined the impact of exercise on obesity outcomes as part of a palliative care program.

Topics PubMed links to this paper include Cholecalciferol, Dietary Supplements, Obesity, Physical Fitness, Overweight, Exercise and Body Mass Index.

The authors tagged it with the keywords menopause, physical performance, vitamin D and women.

What This Means in Plain Language

The paper is a randomized and parallel-group study of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2025 (Women's health (London, England)), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Vitamin D, K2, Magnesium and Zinc in the library

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.