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A Novel Honey Powder-Based Supplement Containing Carbohydrate and Protein Did Not Improve Endurance Performance in Recreationally Trained Cyclists.
Plain-language guide to PMID 40812383 (2025): double-blind randomized controlled trial of Copper (Supplement).
Key Facts
- PMID
- 40812383
- Journal
- International journal of sport nutrition and exercise metabolism
- Year
- 2025
- Study type
- Randomized Controlled Trial
- Authors
- Toniazzo T et al. (9 authors)
- DOI
- 10.1123/ijsnem.2025-0021
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Copper (Supplement), published as a randomized controlled trial.
This study investigated the effect of a novel carbohydrate + protein honey powder (HP) product on endurance cycling performance and physiological and perceptual responses using a double-blind, crossover, counterbalanced, placebo-controlled (PLA) design.
Blood glucose, lactate, pH, bicarbonate, heart rate, ratings of perceived exertion, and side effects were analyzed throughout the 100-min cycling protocol and the 20-min TT.
Who Took Part
The age groups tagged for this paper are young adults and adults, men only.
How the Study Was Run
In design terms this was a randomized, double-blind, placebo-controlled and crossover study.
Random assignment meant chance, not the researchers, decided who got Copper (Supplement) and who got the comparison, which limits bias.
As a double-blind Copper (Supplement) study, the assignments were hidden from both participants and investigators until the end.
A placebo (an inactive look-alike) gave the Copper (Supplement) group a baseline to be compared against.
Each person switched between Copper (Supplement) and the comparison at some point, usually with a gap in between.
What Was Measured
The subject headings attached to it are Bicycling, Dietary Supplements, Physical Endurance, Dietary Carbohydrates, Blood Glucose, Lactic Acid and Athletic Performance.
Author keywords: cycling time trial, dried honey, in vivo testing, plant protein and spray drying.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Copper (Supplement).
The publication is from 2025 (International journal of sport nutrition and exercise metabolism), a journal based in United States.
More context: the Copper (Supplement) compound page, all human trials.
Our Notes on the Compound
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.