Efficacy of levocarnitine combined with tadalafil in treating oligozoospermia and asthenozoospermia: effects on serum sex hormones and sexual function

What Was Tested

The paper reports a study of L-Carnitine in the context of sexual function & libido (women and men), published as a randomized controlled trial.

Who Took Part

According to the abstract, 80 patients were involved.

PubMed indexes the participants as adults, men only.

A total of 80 patients diagnosed with oligozoospermia or asthenozoospermia at their hospital between March 2023 and February 2024 were randomly divided into two groups, A and B, with 40 patients each.

Both groups continued the regimen for 3 months.

How the Study Was Run

The design is described as randomized.

The patients were allocated by chance, so the L-Carnitine group and the comparison group should start out alike.

The timeline in the abstract includes 3 months.

Group A received levocarnitine combined with tadalafil, while Group B was administered levocarnitine alone.

Parameters such as serum sex hormones [testosterone (T), luteinizing hormone (LH), follicle-stimulating hormone (FSH)], sexual function [assessed via the International Index of Erectile Function (IIEF)], and semen quality [including semen volume, sperm concentration, sperm viability, and progressive motility (PR)] were measured pre- and post-treatment.

What Was Measured

The subject headings attached to it are Asthenozoospermia, Tadalafil, Oligospermia, Semen Analysis, Gonadal Steroid Hormones, Luteinizing Hormone and Phosphodiesterase 5 Inhibitors.

Author keywords: Levocarnitine, Oligozoospermia, Serum sex hormones and Sexual function.

What This Means in Plain Language

The paper is a randomized study of L-Carnitine in 80 patients in people with sexual function & libido (women and men) over 3 months.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2025 (Hormones (Athens, Greece)), a journal based in Switzerland.

More context: the L-Carnitine compound page, Sexual function & libido (women and men) research.