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Can correction of low vitamin D status in infancy program for a leaner body composition? A posttrial follow-up study of whole body lean mass in early childhood.

Plain-language guide to PMID 40935152 (2025): clinical trial of Vitamin D, K2, Magnesium and Zinc in 98 infants.

Key Facts

PMID
40935152
Journal
The American journal of clinical nutrition
Year
2025
Study type
Clinical Trial
Authors
Razaghi M et al. (9 authors)
DOI
10.1016/j.ajcnut.2025.09.002
Registered trial
NCT02563015

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a clinical trial.

Vitamin D supplementation is recommended for infants fed human milk and may have a role in supporting the development of lean body mass.

Who Took Part

The abstract describes 98 infants taking part.

By PubMed's age tags, the people studied were infants and young children, both men and women.

Developmental milestones were added at 24 mo (Ages and Stages Questionnaire-3).

How the Study Was Run

The primary outcome was whole body lean mass (dual-energy X-ray absorptiometry).

Other outcomes included: serum 25-hydroxyvitamin D [25(OH)D] (immunoassay), measures of anthropometry, and whole body fat mass and bone mineral content (BMC).

What Was Measured

PubMed files the paper under topics including Body Composition, Bone Density, Cholecalciferol, COVID-19, Dietary Supplements, Vitamin D and Vitamin D Deficiency.

The authors tagged it with the keywords 25-hydroxyvitamin D, developmental milestones, lean mass, pediatrics and postnatal vitamin D supplementation.

What This Means in Plain Language

This is a clinical trial of Vitamin D, K2, Magnesium and Zinc in 98 infants.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2025 (The American journal of clinical nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.