Comparing the Bioavailability of Two Seawater-Derived Magnesium Preparations.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

The purpose of the present study was to compare the bioavailability of magnesium obtained from two different seawater processing methods (hydroxide vs. citrate).

An incremental, 18-h urine magnesium excretion test was used to assess relative magnesium bioavailability.

Why It Was Studied

Previously research has established that seawater contains magnesium in addition to 72 other trace and ultratrace minerals, resulting in better bioavailability than traditional magnesium sources.

Who Took Part

The age groups tagged for this paper are young adults and adults, both men and women.

How the Study Was Run

In design terms this was a randomized, double-blind, placebo-controlled and crossover study.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

Each person switched between Vitamin D, K2, Magnesium and Zinc and the comparison at some point, usually with a gap in between.

What Was Measured

The subject headings attached to it are Biological Availability, Seawater, Magnesium, Magnesium Hydroxide, Dietary Supplements, Magnesium Compounds and Citrates.

The authors tagged it with the keywords natural magnesium, seawater-derived magnesium and water-soluble magnesium.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

The publication is from 2025 (Journal of medicinal food), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.