Effects of a Novel Probiotic Supplement with Weight Gain Intervention on Anthropometry, Body Composition, and Appetite in Underweight Adults: A Randomized Controlled Trial.

What Was Tested

This randomized controlled trial looks at Copper (Supplement).

Primary outcomes included anthropometric measures, including body weight and BMI.

Secondary outcomes included appetite (via visual analog scales), caloric intake, and stool consistency.

Who Took Part

According to the abstract, 95 adults were involved.

The age groups tagged for this paper are teenagers, young adults, adults and middle-aged adults, both men and women.

In this 8-week, double-blind, randomized, placebo-controlled trial, 95 underweight adults (aged 18-60 years) from Mashhad, Iran, were randomized to receive a probiotic supplement (Lacticaseibacillus rhamnosus GG, Lactobacillus acidophilus, Lacticaseibacillus casei; 109 CFU/capsule) or placebo with a 500-kcal surplus diet.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

Because people in this Copper (Supplement) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the adults and researchers unaware of who received Copper (Supplement).

Some adults received a placebo instead of Copper (Supplement), giving a reference point.

What Was Measured

Primary outcomes included anthropometric measures, including body weight and BMI.

Secondary outcomes included appetite (via visual analog scales), caloric intake, and stool consistency.

The subject headings attached to it are Probiotics, Appetite, Body Composition, Energy Intake, Iran, Dietary Supplements and Thinness.

The authors tagged it with the keywords Anthropometry, Lacticaseibacillus, Lactobacillus and weight gain.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Copper (Supplement) in 95 adults.

The publication is from 2025 (Journal of dietary supplements), a journal based in England.

More context: the Copper (Supplement) compound page, all human trials.