The effectiveness of vitamin D supplementation in alleviating diabetes distress among patients with vitamin D deficiency at hospital putrajaya: an open label randomised controlled trial.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

The researchers aim to study the effect of VitD supplementation on DD among patients with VitD deficiency.

Why It Was Studied

METHOD: This was a prospective, open-label randomized intervention study conducted in Putrajaya Hospital using validated Diabetes Distress Scale 17 (DDS17).

The DDS17 addresses four subdomains – A (Emotional burden), B (Physician-related distress), C (Regimen distress) and D (Interpersonal relationship distress).

Who Took Part

The study group was 80 participants.

The age groups tagged for this paper are adults and middle-aged adults, both men and women.

How the Study Was Run

In design terms this was a randomized and open-label study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Being open-label, the Vitamin D, K2, Magnesium and Zinc study did not mask who received what.

What Was Measured

Mean score ≥ 2 is considered DD worthy of clinical attention.

The subject headings attached to it are Vitamin D Deficiency, Dietary Supplements, Vitamin D, Stress, Psychological, Psychological Distress, Malaysia and Vitamins.

The authors tagged it with the keywords Cholecalciferol, Diabetes distress and Supplementation.

What This Means in Plain Language

The paper is a randomized and open-label study of Vitamin D, K2, Magnesium and Zinc in 80 participants.

The publication is from 2025 (Endocrine), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.