Role of vitamin D supplementation in prevention of new onset atrial fibrillation in post-coronary artery bypass graft patients in vitamin D deficient and insufficient populations: a systematic review and meta-analysis.

What It Covers

Researchers studied Vitamin D, K2, Magnesium and Zinc in this meta-analysis publication.

D), via its anti-inflammatory effects and modulation of the renin-angiotensin-aldosterone system (RAAS), may have a cardioprotective role.

Who the Included Studies Covered

By PubMed's age tags, the people studied were middle-aged adults and older adults, both men and women.

Randomized controlled trials and retrospective observational studies involving adult subjects, evaluating Vit.

D deficient and/or insufficient patients who have undergone CABG and received Vit.

How the Review Was Done

Their study was conducted in accordance with the PRISMA 2020 Guidelines.

The electronic databases PubMed, Cochrane Library and Google Scholar were searched from 2014 to 2024.

D supplementation in addition to standard care, compared to patients receiving standard care alone or with placebo, and reporting incidence of new-onset POAF were included.

Statistical analysis was performed using RevMan v5.4 software, utilizing a random effects model with heterogeneity assessed using the I2 statistic.

What Was Measured

Topics PubMed links to this paper include Atrial Fibrillation, Coronary Artery Bypass, Vitamin D, Vitamin D Deficiency, Dietary Supplements, Risk Factors and Incidence.

Author keywords: Cardiac surgery, Coronary artery bypass grafting, Meta-analysis, Postoperative atrial fibrillation and Supplementation.

What This Means in Plain Language

This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2025 (BMC cardiovascular disorders), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.