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Changes in vocal characteristics among children receiving growth hormone treatment due to isolated growth hormone deficiency.
Plain-language guide to PMID 41136565 (2025): observational study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 57 patients.
Key Facts
- PMID
- 41136565
- Journal
- European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
- Year
- 2025
- Study type
- Observational Study
- Authors
- Tuysuz O et al. (8 authors)
- DOI
- 10.1007/s00405-025-09779-x
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as an observational study.
This study investigated the vocal characteristics of children receiving GH treatment.
Who Took Part
The abstract describes 57 patients taking part.
The age groups tagged for this paper are children and teenagers, both men and women.
This analytical, observational cohort study include 57 paediatric patients (33 males and 24 females).
Voice recordings were obtained from all patients at pretreatment, 3 months posttreatment and 6 months posttreatment.
How the Study Was Run
Females and males were divided into two groups: prepubertal and pubertal.
Acoustic analyses were conducted using the Dr.
Speech software, and the fundamental frequency (F0), jitter, shimmer, harmonic-to-noise ratio (HNR), and maximum phonation time (MPT) were evaluated.
What Was Measured
The subject headings attached to it are Human Growth Hormone, Voice Quality, Speech Acoustics, Puberty, Cohort Studies and Voice Disorders.
The authors tagged it with the keywords Acoustic analysis, Fundamental frequency, Jitter and Shimmer.
What This Means in Plain Language
This is an observational study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 57 patients.
Results are reported in around 10 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2025 (European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery), a journal based in Germany.
More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.
Our Notes on the Compound
Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.