The effects of vitamin D combined with thermotherapy and resistance exercise on inflammatory factors, thyroid hormones and MSTN in elderly patients with sarcopenia.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

This study investigated the impact of vitamin D (VD) combined with thermotherapy and resistance exercise (RE) on elderly patients with sarcopenia, thereby offering novel insights into evidence-based management strategies for sarcopenia. 140 sarcopenia patients were admitted between May 2023 and August 2024.

Who Took Part

According to the abstract, 140 patients were involved.

By PubMed's age tags, the people studied were older adults and people over 80, both men and women.

Participants were randomized to receive either VD combined with thermotherapy and resistance exercise (treatment group) or thermotherapy and resistance exercise alone (control group).

How the Study Was Run

In design terms this was a randomized study.

The patients were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Skeletal muscle mass and handgrip strength were evaluated before and after the intervention using a body composition analyzer and a hand dynamometer.

In addition, the levels of blood glucose, blood lipids, inflammatory factors and thyroid hormones were measured.

What Was Measured

PubMed files the paper under topics including Sarcopenia, Resistance Training, Vitamin D, Thyroid Hormones, Muscle, Skeletal, Myostatin and Hyperthermia, Induced.

Author keywords: Inflammatory factors and Resistance exercise.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 140 patients.

The publication is from 2025 (Pakistan journal of pharmaceutical sciences), a journal based in Pakistan.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.