Effectiveness of Combined Vitamin D and Iron Supplementation on Iron Status in Children with Iron Deficiency Anemia: A Randomized Controlled Trial.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc in the context of anemia, published as a randomized controlled trial.

Iron deficiency can impair vitamin D absorption, yet the interaction between these deficiencies remains unclear.

Who Took Part

According to the abstract, 250 patients were involved.

By PubMed's age tags, the people studied were infants, young children and children, both men and women.

An open-label, randomized controlled trial was conducted at four outpatient clinics and Dr.

Of 250 assessed patients, 67 met the inclusion criteria.

How the Study Was Run

In design terms this was a randomized and open-label study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Nothing was hidden in this open-label Vitamin D, K2, Magnesium and Zinc study: the patients and staff both knew the treatment.

Wahidin Sudirohusodo Hospital, Makassar, Indonesia.

Treatment lasted 4 weeks, and iron status was evaluated pre- and post-treatment.

What Was Measured

The subject headings attached to it are Anemia, Iron-Deficiency, Vitamin D, Iron, Ferritins and Dietary Supplements.

The authors tagged it with the keywords children.

What This Means in Plain Language

The paper is a randomized and open-label study of Vitamin D, K2, Magnesium and Zinc in 250 patients in people with anemia.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2025 (The journal of medical investigation : JMI), a journal based in Japan.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Anemia research.