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Effect of magnesium sulfate in patients with preeclampsia with severe features on gastric antrum cross-sectional area: a prospective observational study.
Plain-language guide to PMID 41240485 (2026): observational study of Vitamin D, K2, Magnesium and Zinc in 31 patients.
Key Facts
- PMID
- 41240485
- Journal
- International journal of obstetric anesthesia
- Year
- 2026
- Study type
- Observational Study
- Authors
- Helmy MA et al. (6 authors)
- DOI
- 10.1016/j.ijoa.2025.104816
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this observational study publication.
While the systemic effects of magnesium sulfate administration are well described, its effects on gastric motility and aspiration risk remain underexplored.
The researchers evaluated the effect of magnesium sulfate administration on the gastric antrum cross-sectional area (CSA) in the setting of preeclampsia with severe features.
Who Took Part
The study group was 31 patients.
By PubMed's age tags, the people studied were adults, women only.
How the Study Was Run
Gastric ultrasound was performed at baseline (pre-bolus) and 10- and 20-min post-bolus.
Serum magnesium levels were measured at baseline and 20 min post-bolus.
The primary outcome was the change in gastric CSA from baseline to 20 min post-bolus.
What Was Measured
The researchers evaluated the effect of magnesium sulfate administration on the gastric antrum cross-sectional area (CSA) in the setting of preeclampsia with severe features.
The subject headings attached to it are Magnesium Sulfate, Pre-Eclampsia, Pyloric Antrum and Ultrasonography.
What This Means in Plain Language
This is an observational study of Vitamin D, K2, Magnesium and Zinc in 31 patients.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2026 (International journal of obstetric anesthesia), a journal based in Netherlands.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.