The effect of early postpartum vitamin d and e supplementation on uterine after pain: a double-blind randomized clinical trial.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Uterine after pain is a common yet under-addressed postpartum complaint.

Iranian Registry of Clinical Trials (IRCT): IRCT20220313054270N1.

Who Took Part

By PubMed's age tags, the people studied were adults, women only.

The duration of pain was measured via the Cox Menstrual Symptom Scale (CMSS).

How the Study Was Run

The design is described as randomized, double-blind, placebo-controlled and parallel-group.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

The Vitamin D, K2, Magnesium and Zinc group and the comparison group ran side by side rather than switching.

This double-blind, parallel-group randomized clinical trial was conducted between October and December 2022 at Shahid Mobini Hospital in Sabzevar, Iran.

Pain intensity was assessed via the visual analog scale (VAS), beginning 2 h after delivery and subsequently at 6-hour intervals across eight time points.

What Was Measured

PubMed files the paper under topics including Vitamin E, Iran, Vitamin D, Dietary Supplements, Postpartum Period, Pain Measurement and Vitamins.

The authors tagged it with the keywords Multiparous women, Pain management, Postpartum after pain and Randomized clinical trial.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2025 (BMC women's health), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.