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Risk of hypermagnesemia in patients with eating disorders taking magnesium oxide preparations: a retrospective study.
Plain-language guide to PMID 41258365 (2025): observational study of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 41258365
- Journal
- Eating and weight disorders : EWD
- Year
- 2025
- Study type
- Observational Study
- Authors
- Uematsu M et al. (13 authors)
- DOI
- 10.1007/s40519-025-01796-3
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as an observational study.
This study examined the incidence of hypermagnesemia in patients with eating disorders, its associations with renal function, body mass index, and magnesium oxide use, and the correlation between different methods of estimating renal function and serum magnesium levels.
Why It Was Studied
Level III, well-designed cohort or case-control analytic studies.
Who Took Part
The age groups tagged for this paper are teenagers, young adults, adults and middle-aged adults, women only.
This retrospective cohort study was conducted in female patients with eating disorders treated at Nagoya University Hospital between January 2018 and December 2022.
Patients diagnosed as eating disorders, based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision, were included.
How the Study Was Run
Serum magnesium levels, estimated glomerular filtration rate, body mass index, and magnesium oxide prescriptions were collected.
Linear mixed-effects models were used to analyze factors affecting serum magnesium levels.
Renal function screening methods were compared in underweight patients.
What Was Measured
Level III, well-designed cohort or case-control analytic studies.
The subject headings attached to it are Body Mass Index, Feeding and Eating Disorders, Glomerular Filtration Rate, Magnesium, Magnesium Oxide, Risk Factors and Thinness.
The authors tagged it with the keywords Anorexia nervosa, Hypermagnesemia and Renal function.
What This Means in Plain Language
This is an observational study of Vitamin D, K2, Magnesium and Zinc.
The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2025 (Eating and weight disorders : EWD), a journal based in Germany.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.