Vitamin D Supplementation Adjunct to Home-Based Electrical Stimulation Exercise Program Versus Passive Movement Training in Chronic SCI: Individual Results From Trial Under Accrual.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Neurogenic osteoporosis as a result of bone demineralization is a well-known complication after spinal cord injury (SCI).

Who Took Part

By PubMed's age tags, the people studied were adults and middle-aged adults, men only.

Six men with motor complete SCI ranging from C8 to T10 were randomized into either 9 months of vit D+ES-Excs or vit D+PMT groups.

How the Study Was Run

The researchers set it up as a randomized study.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

MRI, DXA, and blood biomarkers were captured at the beginning of the study (baseline), 4.5 months (post-intervention 1), and 9 months after training (post-intervention 2).

What Was Measured

The subject headings attached to it are Vitamin D, Spinal Cord Injuries, Electric Stimulation Therapy, Exercise Therapy, Bone Density, Dietary Supplements and Magnetic Resonance Imaging.

The authors tagged it with the keywords BMD, electrical stimulation, home-based training, spinal cord injury, telehealth and trabecular bone.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2025 (Topics in spinal cord injury rehabilitation), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.