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Vitamin D Status and Clinical Outcomes in Pediatric Idiopathic Nephrotic Syndrome: A Prospective Observational Study from North India.

Plain-language guide to PMID 41288469 (2026): observational study of Vitamin D, K2, Magnesium and Zinc in 60 children.

Key Facts

PMID
41288469
Journal
Annals of African medicine
Year
2026
Study type
Observational Study
Authors
Alim M et al. (6 authors)
DOI
10.4103/aam.aam_530_25

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as an observational study.

To evaluate Vitamin D status in children with idiopathic nephrotic syndrome and assess its association with remission time and relapse patterns.

Why It Was Studied

Idiopathic nephrotic syndrome frequently presents with Vitamin D deficiency due to urinary losses of Vitamin D-binding protein.

The relationship between Vitamin D status and clinical outcomes remains incompletely understood.

Who Took Part

The study group was 60 children.

PubMed indexes the participants as infants, young children, children and teenagers, both men and women.

This prospective observational study (October 2022-March 2024) included 60 children aged 1-14 years with idiopathic nephrotic syndrome at a tertiary care center in North India.

The study involved 60 patients divided into supplemented (Group I, n = 30) and control (Group II, n = 30) groups.

How the Study Was Run

Primary outcomes included baseline Vitamin D status, time to remission, and 6-month relapse rates.

What Was Measured

The relationship between Vitamin D status and clinical outcomes remains incompletely understood.

Topics PubMed links to this paper include Nephrotic Syndrome, Vitamin D Deficiency, India, Vitamin D, Recurrence and Remission Induction.

Author keywords: Children, Enfants, carence en vitamine D, néphrologie pédiatrique, pediatric nephrology and proteinuria.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc in 60 children.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2026 (Annals of African medicine), a journal based in India.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.