The effect of the magic glove technique on pain and anxiety in children during leuprolide injection: A quasi-experimental study

What Was Tested

This randomized controlled trial paper looks at Leuprolide.

Leuprolide injections, commonly used for precocious puberty, may cause considerable distress.

Who Took Part

The abstract describes 60 children taking part.

PubMed indexes the participants as children, both men and women.

A quasi-experimental study was conducted on 60 children referred to the injection unit of the emergency department at Amir-al-Momenin Hospital, Semnan, Iran, between March and June 2024.

Participants were recruited by convenience sampling and assigned to intervention (n = 30) and control (n = 30) groups using block randomization.

How the Study Was Run

In design terms this was a randomized study.

Because people in this Leuprolide study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

The control group received routine care, while the intervention group underwent the magic glove technique before injection.

Pain intensity (Wong-Baker FACES Pain Rating Scale) and anxiety levels (Observational Scale of Behavioral Distress-Revised) were recorded.

Data were analyzed with ANOVA and ANCOVA in Stata 14.

What Was Measured

Topics PubMed links to this paper include Anxiety, Leuprolide, Pain Measurement, Pain Management, Iran, Pain and Puberty, Precocious.

Author keywords: Children, Injection and Magic glove.

What This Means in Plain Language

The paper is a randomized study of Leuprolide in 60 children.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2026 (Journal of pediatric nursing), a journal based in United States.

More context: the Leuprolide compound page, all human trials.