Effect of vitamin D as Nutrition Supplement on Patients with Prolonged Ventilation due to Ventilator Associated Pneumonia and Sepsis Followed Severe Traumatic Lung Contusion: A Randomized Controlled Trial.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).

The secondary objectives were to assess its impact on duration of mechanical ventilation, length of ICU stay, and mortality.

Who Took Part

The study group was 80 patients.

PubMed indexes the participants as adults, middle-aged adults and older adults, both men and women.

This prospective, double-blinded randomized controlled trial included 80 adult ICU patients with severe traumatic lung contusion who remained mechanically ventilated for 10 consecutive days and subsequently developed VAP and sepsis (Murray score >4, CPIS >6, SOFA score > 10, excluding GCS).

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

The patients were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Blinding on both sides kept the patients and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

What Was Measured

The subject headings attached to it are Contusions, Dietary Supplements, Intensive Care Units, Length of Stay, Lung Injury, Pneumonia, Ventilator-Associated and Respiration, Artificial.

The authors tagged it with the keywords Nutrition, Sepsis, VAP and Vitamin D.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in 80 patients.

Its findings take up roughly 3 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2026 (La Clinica terapeutica), a journal based in Italy.

More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.