← Human Trials & Peer-Reviewed Studies
Higher Prevalence of Inadequate Vitamin D Intake in Toddlers Not Consuming a Vitamin D Supplement in Vancouver, Canada.
Plain-language guide to PMID 41616856 (2026): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).
Key Facts
- PMID
- 41616856
- Journal
- The Journal of nutrition
- Year
- 2026
- Study type
- Randomized Controlled Trial
- Authors
- Wiedeman AM et al. (6 authors)
- DOI
- 10.1016/j.tjnut.2026.101382
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in this randomized controlled trial publication.
To determine vitamin D intake and status in a group of Canadian toddlers.
Why It Was Studied
Vitamin D is required for growth and development.
However, little is known about dietary intake and status during early childhood.
Who Took Part
By PubMed's age tags, the people studied were infants and young children, both men and women.
This is a secondary analysis of data from toddlers enrolled in a double-blind randomized controlled trial of fatty acid supplementation, between ages 1 y and 2 y in Vancouver (latitude 49°N), Canada.
Dietary information was collected using a 3-d food record, and supplement use by questionnaire.
How the Study Was Run
In design terms this was a randomized and double-blind study.
The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.
Plasma 25-hydroxyvitamin D3 (25OHD) concentrations were quantified by liquid chromatography-tandem mass spectrometry.
Blood sampling was dichotomized by season as winter (September to February) and summer (March to August).
What Was Measured
The subject headings attached to it are Dietary Supplements, Vitamin D, Vitamin D Deficiency, Seasons, Prevalence, British Columbia and Diet.
Author keywords: fortified foods, nutritional status and young children.
What This Means in Plain Language
The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).
Its findings take up roughly 10 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2026 (The Journal of nutrition), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.
Our Notes on the Compounds
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.