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Repeat Behavioral Counseling, With and Without Combination Nicotine Replacement Therapy, for Smoking Cessation Among People With HIV in South Africa.
Plain-language guide to PMID 41689618 (2026): randomized controlled trial of Therapeutic nicotine (patch, non-peptide).
Key Facts
- PMID
- 41689618
- Journal
- AIDS and behavior
- Year
- 2026
- Study type
- Randomized Controlled Trial
- Authors
- Keke C et al. (11 authors)
- DOI
- 10.1007/s10461-026-05064-y
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Therapeutic nicotine (patch, non-peptide), published as a randomized controlled trial.
However, evidence is lacking for repeat treatment outcomes among people with HIV (PWH) who smoke in low-resource settings.
The researchers evaluated outcomes among participants (n = 384) who were provided a second round of treatment after initial treatment failure in a randomized controlled trial of behavioral counseling (BC) with or without combination nicotine replacement therapy (nicotine patches and gum, cNRT).
Who Took Part
By PubMed's age tags, the people studied were adults and middle-aged adults, both men and women.
How the Study Was Run
The design is described as randomized.
Because people in this Therapeutic nicotine (patch, non-peptide) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
What Was Measured
However, evidence is lacking for repeat treatment outcomes among people with HIV (PWH) who smoke in low-resource settings.
The researchers evaluated outcomes among participants (n = 384) who were provided a second round of treatment after initial treatment failure in a randomized controlled trial of behavioral counseling (BC) with or without combination nicotine replacement therapy (nicotine patches and gum, cNRT).
Topics PubMed links to this paper include Nicotine Replacement Therapy, Smoking Cessation, HIV Infections, Counseling, South Africa, Behavior Therapy and Tobacco Use Cessation Devices.
Author keywords: Behavioral counseling, People with HIV and Repeat treatment.
What This Means in Plain Language
The paper is a randomized study of Therapeutic nicotine (patch, non-peptide).
The publication is from 2026 (AIDS and behavior), a journal based in United States.
More context: the Therapeutic nicotine (patch, non-peptide) compound page, all human trials.
Our Notes on the Compound
Therapeutic nicotine (patch, non-peptide): Pure nicotine as a signaling tool, separated from smoking and vaping.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.