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A randomized trial of iron- and zinc-biofortified pearl millet-based complementary feeding in children aged 12-18 months living in urban slums.

Plain-language guide to PMID 41740296 (2026): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 223 children.

Key Facts

PMID
41740296
Journal
Clinical nutrition (Edinburgh, Scotland)
Year
2026
Study type
Randomized Controlled Trial
Authors
Mehta S et al. (17 authors)
DOI
10.1016/j.clnu.2025.11.002
Registered trial
NCT02233764

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

Biofortification of staple crops with higher concentrations of micronutrients via traditional breeding methods is a sustainable strategy and can possibly complement fortification and other interventions to target micronutrient deficiencies in low resource settings, particularly among populations such as children.

Why It Was Studied

This trial is registered with Clinicaltrials.gov (ID: NCT02233764), and Clinical Trials Registry of India (ID: REF/2014/10/007731).

Who Took Part

The study group was 223 children.

By PubMed's age tags, the people studied were infants, both men and women.

Hemoglobin, serum ferritin, and plasma zinc concentrations as well as growth indicators (length, weight, mid-upper arm circumferences, triceps and subscapular skinfolds) were evaluated at enrollment and throughout the trial.

How the Study Was Run

The design is described as randomized.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

World Health Organization (WHO) anthropometric Z-scores were calculated using WHO growth standards.

Primary outcomes were hemoglobin and serum ferritin concentrations, and growth, defined as WHO Z-scores.

An intent-to-treat approach was used for analyses.

What Was Measured

PubMed files the paper under topics including Biofortification, Ferritins, Food, Fortified, Hemoglobins, India, Infant Nutritional Physiological Phenomena and Iron.

The authors tagged it with the keywords Children, Complementary foods, Growth and Urban slums.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 223 children.

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2026 (Clinical nutrition (Edinburgh, Scotland)), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.