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Combined effect of pulmonary rehabilitation and vitamin D supplementation on pulmonary function tests in asthma patients.

Plain-language guide to PMID 41860253 (2026): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 90 adults.

Key Facts

PMID
41860253
Journal
The Journal of asthma : official journal of the Association for the Care of Asthma
Year
2026
Study type
Randomized Controlled Trial
Authors
Fatima A et al. (4 authors)
DOI
10.1080/02770903.2026.2647908

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

To evaluate the Combined Effect of Pulmonary Rehabilitation and Vitamin D Supplementation on Pulmonary Function Tests in Asthma Patients.

Who Took Part

The abstract describes 90 adults taking part.

By PubMed's age tags, the people studied were adults and middle-aged adults, both men and women.

In this 12-week comparative interventional study, 90 adults (aged 30-55 years) with mild to moderate asthma and serum 25(OH)D < 30 ng/mL were randomized into three groups (n = 30 each): Group A (PR + vitamin D), Group B (PR only), and Group C (vitamin D only).

How the Study Was Run

The researchers set it up as a randomized study.

The adults were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Pulmonary function tests (FEV1, FVC, FEV1/FVC) and serum 25(OH)D levels were measured pre- and post-intervention.

Within-group and between-group differences were analyzed using paired t-tests and ANOVA with Tukey post-hoc tests.

What Was Measured

PubMed files the paper under topics including Asthma, Dietary Supplements, Vitamin D, Respiratory Function Tests, Cholecalciferol, Forced Expiratory Volume and Exercise Therapy.

The authors tagged it with the keywords airway inflammation, pulmonary function tests, pulmonary rehabilitation and vitamin D supplementation.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 90 adults.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2026 (The Journal of asthma : official journal of the Association for the Care of Asthma), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.