High-dose vs standard-dose vitamin D and sleep in early childhood: A randomized clinical trial.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

There are no randomized trials on the association in childhood.

Who Took Part

The age groups tagged for this paper are infants and young children, both men and women.

Blood 25(OH)D was analyzed and parents completed questionnaires at 11.7 (SD = 0.7) and at 26.0 (SD = 3.0) months (Brief Infant Sleep Questionnaire, Sleep Disturbance Scale for Children).

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

VIDI-study [Vitamin D Intervention in Infants] is a double-blind randomized clinical trial.

Maternal 25(OH)D was analyzed at mean 11.3 (SD = 2.2) gestational weeks.

The researchers used regression models adjusted for season of birth, breastfeeding, gestational age, parental education, and mother's age, body-mass-index, smoking and sleep.

What Was Measured

Topics PubMed links to this paper include Vitamin D, Sleep, Dietary Supplements, Surveys and Questionnaires, Cholecalciferol, Vitamin D Deficiency and Sleep Wake Disorders.

The authors tagged it with the keywords 25(OH)D, Children, Sleep disorders and Sleep problems.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2026 (Sleep medicine), a journal based in Netherlands.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.