Carnosine-Enriched Chicken Meat Improves Microvascular Function and Anti-Inflammatory Phenotype in Patients with Chronic Coronary Syndrome

What Was Tested

Researchers studied Carnosine in this randomized controlled trial publication.

This study investigated the effect of the consumption of carnosine-enriched chicken meat on endothelium-dependent and independent microvascular reactivity and inflammatory mediators in patients with chronic coronary syndrome (CCS).

Who Took Part

According to the abstract, 38 participants were involved.

The age groups tagged for this paper are middle-aged adults and older adults, both men and women.

In total, 38 CCS participants were randomized to two groups: the Control group (N = 19), who consumed regular chicken meat, and the Carnosine group (N = 19), who consumed carnosine-enriched chicken meat for 3 weeks.

How the Study Was Run

In design terms this was a randomized study.

Random assignment meant chance, not the researchers, decided who got Carnosine and who got the comparison, which limits bias.

A time span of 3 weeks appears in the methods.

Skin microvascular reactivity in response to vascular occlusion (PORH), acetylcholine (ACh ID), sodium nitroprusside (SNP ID), and local thermal hyperemia (LTH) was measured.

Arterial blood pressure (BP), heart rate (HR), biochemical parameters, anti- and proinflammatory cytokine levels, and markers of oxidative stress were assessed before and after the intervention.

What Was Measured

The subject headings attached to it are Anti-Inflammatory Agents, Blood Pressure, Carnosine, Chickens, Chronic Disease, Cytokines and Endothelium, Vascular.

Author keywords: chronic coronary syndrome, functional food and microcirculation.

What This Means in Plain Language

The paper is a randomized study of Carnosine in 38 participants over 3 weeks.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2026 (Nutrients), a journal based in Switzerland.

More context: the Carnosine compound page, all human trials.