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Vitamin D in the prevention of left ventricular remodelling after an acute myocardial infarction: a randomized clinical trial.
Plain-language guide to PMID 41942544 (2026): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 93 patients.
Key Facts
- PMID
- 41942544
- Journal
- Scientific reports
- Year
- 2026
- Study type
- Randomized Controlled Trial
- Authors
- Tuñón J et al. (28 authors)
- DOI
- 10.1038/s41598-026-45330-6
- Registered trial
- NCT02548364
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.
No clinical trial has yet assessed the effect of vitamin D on patients experiencing ST-segment elevation myocardial infarction (STEMI).
Who Took Part
The study group was 93 patients.
PubMed indexes the participants as middle-aged adults and older adults, both men and women.
Sixty-five patients were allocated to calcifediol and 28 to placebo.
How the Study Was Run
In design terms this was a randomized, double-blind, placebo-controlled and multicenter study.
The patients were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
Neither the patients nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.
Some patients received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.
Running at several centres spread the Vitamin D, K2, Magnesium and Zinc study over different clinics and patient groups.
What Was Measured
No clinical trial has yet assessed the effect of vitamin D on patients experiencing ST-segment elevation myocardial infarction (STEMI).
Topics PubMed links to this paper include Ventricular Remodeling, Calcifediol, Fibroblast Growth Factor-23, Vitamin D, Magnetic Resonance Imaging, ST Elevation Myocardial Infarction and Myocardial Infarction.
The authors tagged it with the keywords Acute myocardial infarction, Cardiac magnetic resonance imaging and Remodelling.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 93 patients.
The publication is from 2026 (Scientific reports), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.