Impact of vitamin D status and supplementation on exploratory inflammatory biomarkers in preschoolers with asthma.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

To measure the association between serum 25-hydroxyvitamin D (25(OH)D) and inflammatory biomarkers and the impact of vitamin D supplementation on these biomarkers.

Who Took Part

By PubMed's age tags, the people studied were infants and young children, both men and women.

How the Study Was Run

In design terms this was a randomized and placebo-controlled study.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Some participants received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

Serum 25(OH)D and C-reactive protein (CRP) were measured at baseline, 3.5 months, and 7 months, whereas blood cells were measured at baseline and 7 months.

Primary outcomes were CRP across time points and change from baseline in CRP at 3.5 and 7 months, analyzed using generalized estimating equation and mixed-effects models.

What Was Measured

PubMed files the paper under topics including Asthma, Biomarkers, C-Reactive Protein, Cholecalciferol, Dietary Supplements, Inflammation and Neutrophils.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2026 (Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.