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Differential and Dose-Dependent Redistribution of Vitamin D Metabolites After Acute High-Intensity Exercise in Mixed Martial Arts Athletes and Untrained Men: Pilot Study.
Plain-language guide to PMID 41978112 (2026): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 41978112
- Journal
- Nutrients
- Year
- 2026
- Study type
- Randomized Controlled Trial
- Authors
- Dzik KP et al. (7 authors)
- DOI
- 10.3390/nu18071061
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.
Blood samples were collected at rest and 30 min and 24 h post-exercise to assess vitamin D metabolites, VDBP, bioavailable and free 25(OH)D3, interleukin-6, and lactate.
Why It Was Studied
Background/Objectives: Acute high-intensity exercise may transiently alter circulating vitamin D metabolites.
Methods: Thirty-four healthy young men participated, comprising 22 mixed martial arts (MMA) athletes and 12 untrained controls.
Who Took Part
The age groups tagged for this paper are young adults and adults, men only.
How the Study Was Run
In design terms this was a randomized, placebo-controlled and pilot study.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Some participants received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.
It is described as a pilot, a small early test of whether a larger Vitamin D, K2, Magnesium and Zinc study would be practical.
What Was Measured
Before and after the intervention, participants performed a supramaximal anaerobic exercise protocol (3 × 30 s Wingate tests).
PubMed files the paper under topics including Pilot Projects, Martial Arts, Dietary Supplements, Athletes, Cholecalciferol, Vitamin D-Binding Protein and Exercise.
Author keywords: anaerobic performance, high-intensity exercise, mixed martial arts and vitamin D3.
What This Means in Plain Language
The paper is a randomized, placebo-controlled and pilot study of Vitamin D, K2, Magnesium and Zinc.
The publication is from 2026 (Nutrients), a journal based in Switzerland.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.