Clinical efficacy of a stannous fluoride toothpaste stabilized with zinc phosphate in reducing supragingival calculus formation compared to a sodium monofluorophosphate toothpaste: A randomized controlled trial.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

Who Took Part

The age groups tagged for this paper are adults and middle-aged adults, both men and women.

Healthy adults (n= 100) with a baseline Volpe-Manhold Calculus Index score ≥7.0 were randomized to either the stannous fluoride (Test) or sodium monofluorophosphate (Control) group.

How the Study Was Run

The researchers set it up as a randomized, double-blind and parallel-group study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

Groups ran in parallel: each of the participants stayed in one arm throughout.

A randomized, single-center, double-blind, parallel-group study was conducted in Bangkok, Thailand.

Supragingival calculus was assessed using the Volpe-Manhold Calculus Index.

What Was Measured

Topics PubMed links to this paper include Dental Calculus, Fluorides, Phosphates, Tin Fluorides, Toothpastes and Zinc Compounds.

What This Means in Plain Language

The paper is a randomized, double-blind and parallel-group study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2026 (American journal of dentistry), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.