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Magnesium-Rich Mineral Water Improves Stool Consistency and Bowel Habits in Healthy Subjects: A Randomized Controlled Trial.

Plain-language guide to PMID 42286933 (2026): parallel-group randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 40 subjects.

Key Facts

PMID
42286933
Journal
Neurogastroenterology and motility
Year
2026
Study type
Randomized Controlled Trial
Authors
Yoneda H et al. (15 authors)
DOI
10.1111/nmo.70378

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Magnesium-rich mineral water influences stool consistency and bowel habits.

However, randomized controlled trials directly comparing magnesium-rich mineral water with soft water using standardized bowel outcomes remain limited.

Who Took Part

The abstract describes 40 subjects taking part.

By PubMed's age tags, the people studied were young adults, adults and middle-aged adults, both men and women.

This single-center, randomized, parallel-group trial enrolled 40 healthy subjects who did not meet Rome IV criteria for chronic constipation or irritable bowel syndrome.

How the Study Was Run

In design terms this was a randomized and parallel-group study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Groups ran in parallel: each of the subjects stayed in one arm throughout.

What Was Measured

However, randomized controlled trials directly comparing magnesium-rich mineral water with soft water using standardized bowel outcomes remain limited.

The subject headings attached to it are Mineral Waters, Magnesium, Defecation, Constipation, Feces and Healthy Volunteers.

The authors tagged it with the keywords Bristol stool form scale, bowel movements, healthy subjects and randomized controlled trial.

What This Means in Plain Language

The paper is a randomized and parallel-group study of Vitamin D, K2, Magnesium and Zinc in 40 subjects.

The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2026 (Neurogastroenterology and motility), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.