Association of Serum 25-Hydroxyvitamin D and Vitamin D Receptor with Hyperthyroidism: A Case-Control Observational Study from South India.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this observational study publication.

To evaluate the association of serum 25(OH)D and VDR levels with hyperthyroidism and to examine their relationship with thyroid function parameters and thyroid autoantibodies.

Why It Was Studied

However, data on serum 25-hydroxyvitamin D (25(OH)D) and vitamin D receptor (VDR) levels in hyperthyroidism from South India remain limited.

Who Took Part

The study group was 188 participants.

PubMed indexes the participants as adults and middle-aged adults, both men and women.

This case-control study included 188 participants recruited from a tertiary care teaching hospital in South India between September 2022 and April 2024.

The study comprised 80 patients with hyperthyroidism and 108 age- and sex-matched healthy controls.

How the Study Was Run

Serum thyroid hormones, thyroid autoantibodies, biochemical parameters, 25(OH)D, and VDR were measured using standardized laboratory methods.

Comparisons between groups were made with appropriate parametric or non-parametric tests based on the nature of the data, while relationships between variables were examined using Pearson's correlation coefficient.

What Was Measured

However, data on serum 25-hydroxyvitamin D (25(OH)D) and vitamin D receptor (VDR) levels in hyperthyroidism from South India remain limited.

The subject headings attached to it are Hyperthyroidism, Case-Control Studies, Vitamin D, Receptors, Calcitriol, India, Autoantibodies and Thyroid Hormones.

The authors tagged it with the keywords Hyperthyroidism; 25-Hydroxyvitamin D; Vitamin D receptor; Thyroid hormones; Thyroid autoantibodies.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc in 188 participants.

The abstract goes on to report its results in about 9 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2026 (La Clinica terapeutica), a journal based in Italy.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.