Evaluation of teriparatide as a promoter of mandibular fracture healing: An observational clinical study

What Was Tested

This observational study paper looks at Teriparatide.

The objective of this study was to evaluate the role of teriparatide in promoting mandibular fracture healing.

The groups were followed up and reviewed for a period of 6 weeks to assess fracture healing.

Who Took Part

The abstract describes 12 patients taking part.

PubMed indexes the participants as adults and middle-aged adults, both men and women.

The secondary outcome parameters were requirement of analgesics and mouth opening.

How the Study Was Run

The primary outcome parameters were postoperative pain, levels of serum osteocalcin and pro collagen type 1 N-terminal propeptide (P1NP) and bone density on CT.

Pain was assessed using numerical pain rating scale.

Serum osteocalcin and P1NP were assessed pre-operatively and on the 30th post-operative day.

Bone density was assessed pre-operatively and on the 6th post-operative week.

The data was analyzed for descriptive and analytical statistics (comparison of means and proportions).

What Was Measured

The subject headings attached to it are Teriparatide, Mandibular Fractures, Fracture Healing, Osteocalcin, Bone Density, Procollagen and Peptide Fragments.

What This Means in Plain Language

This is a observational study of Teriparatide in 12 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2026 (Chinese journal of traumatology = Zhonghua chuang shang za zhi), a journal based in China.

More context: the Teriparatide compound page, all human trials.